Description
Corosolic acid is derived from the extract of the leaves of Lagerstroemia speciosa (L.) Pers.. The results of in vitro and in vivo experiments show that corosolic acid promotes the absorption and utilization of glucose by cells by stimulating the transport of glucose, thereby achieving its hypoglycemic effect. The excitatory effect of corosolic acid on glucose transport is similar to that of insulin, therefore, corosolic acid is also called plant insulin.
Corosolic acid also has weight loss, anti-inflammatory, antiviral and anti-cardiovascular effects. Clinical studies have found that taking the drug can regulate insulin and blood sugar levels in the body, with a clear trend of weight loss (monthly average weight loss of 0.908-1.816Kg) ), the process is relatively slow and does not require a diet. Corosolic acid also has a variety of other biological activities, such as a significant inhibitory effect on TPA-induced inflammatory response, and its anti-inflammatory effect is stronger than the marketed anti-inflammatory drug indomethacin; it also has DNA polymerase inhibitory activity, And it has inhibitory effect on the growth of various tumor cells. At present, a variety of health care products have been developed at home and abroad.
Corosolic acid COA
| Item | Specification | Method | Result |
| Assay | Corosolic Acid>10% | HPLC | Conforms |
| Appearance | Fine powder | Organoleptic | Conforms |
| Color | Brown green | Organoleptic | Conforms |
| Odour | Characteristic | Organoleptic | Conforms |
| Mesh Size | 95% through 60 mesh size | USP32<786> | Conforms |
| Drying Method | spray drying | spray drying | Conforms |
| Ash | ≤5.0% | Eur.Ph.6.0[2.4.16] | 3.26% |
| Loss on Drying | ≤5.0% | Eur.Ph.6.0[2.4.16] | 1.39% |
| Contaminants | |||
| Pesticides Residue | Meet USP32<561> | USP32<561> | Conforms |
| Lead(Pb) | ≤2.0mg/kg | Eur.Ph6.0<2.2.58>ICP-MS | Conforms |
| Arsenic(As) | ≤2.0mg/kg | Eur.Ph6.0<2.2.58>ICP-MS | Conforms |
| Cadmium(Cd) | ≤1.0mg/kg | Eur.Ph6.0<2.2.58>ICP-MS | Conforms |
| Mercury(Hg) | ≤0.01mg/kg | Eur.Ph6.0<2.2.58>ICP-MS | Conforms |
| Microbiological | |||
| Total Plate Count | ≤1000cfu/g | USP30<61> | Conforms |
| Yeast &Mold | ≤300cfu/g | USP30<61> | Conforms |
| E.Coli. | Negative | USP30<62> | Conforms |
| Salmonella | Negative | USP30<62> | Conforms |
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