Description
Melatonin is one of the hormones secreted by the brain’s pineal gland. Melatonin belongs to indole heterocyclic compounds, its chemical name is N-acetyl-5-methoxytryptamine, also known as pineal hormone, melatonin, melatonin. After melatonin is synthesized, it is stored in the pineal body, and sympathetic nerve excitation innervates the pineal cells to release melatonin. The secretion of melatonin has a distinct circadian rhythm, with suppressed secretion during the day and active secretion at night. The well-known functions of melatonin are mainly to improve sleep quality, shorten the wake-up time before going to bed and fall asleep time, significantly reduce the number of awakenings during sleep, shorten the light sleep stage, prolong the deep sleep stage, and decrease the next morning wake-up threshold. There is a strong function of adjusting the time difference.
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Melatonin COA
| Items | Specifications | Results |
| Appearance | White to Off-white crystalline powder | Complies |
| Identification(A)-IR | Pass Test | Complies |
| Identification(B)-HPLC | Pass Test | Complies |
| Loss on drying | NMT 0.5% | 0.1% |
| Residue on ignition | NMT0.1% | 0.1% |
| Chloride | NMT 0.02% | 0.01% |
| Heavy metals | NMT l0ppm | Complies |
| Lead | NMT 0.5ppm | Complies |
| Arsenic | NMT 0.5ppm | Complies |
| Cadmium | NMT 0.1 ppm | Complies |
| Mercury | NMT 0.1 ppm | Complies |
| Assay | >99.0% | 99.4% |
| Total impurities | NMT 0.5% | 0.1% |
| Individual impurity | NMT 0.1% | 0.1% |
| Microbiological Test | ||
| Total Plate Count | NMT l000CFU/g | Complies |
| Yeast & Mold | NMT 50CFU/g | Complies |
| Coliforms | NMT l0CFU/g | Complies |
| E.Coli. | Negative | Complies |
| Salmonella | Negative | Complies |
| Staphylococcus | Negative | Complies |
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