Description
Nicotinamide (nicotinamide; niacinamide), also known as nicotinamide, is an amide compound of niacin. Niacinamide is a derivative of vitamin B3 and is recognized as a skin anti-aging ingredient in the field of cosmetic dermatology. Its most important effect in skin anti-aging is to lighten and prevent dull skin tone, yellowing, and sallowness caused by the early aging process of the skin. Of course, the contribution of niacinamide to the skin is much more than that, and it can also repair the damaged stratum corneum lipid barrier and improve skin resistance. There are also some effects that may be overlooked by people, that is, the deep water-locking effect of niacinamide. Therefore, skin care products containing niacinamide have strong water-locking and moisturizing effects. With age, the skin becomes dull and dull, and topical niacinamide can improve this dullness. Enlarged pores are one of the skin texture problems. Topical niacinamide can reduce the production of fatty acids and triglycerides in sebum, which can shrink pores and reduce the severity of acne when it occurs.
Nicotinamide COA
| ITEM | SPECIFICATION | METHOD REFERENCE | RESULTS |
| Assay % ww (On Dry Basis(ByHPLC) | 98.5-101.5% | As per USP 37 | 99.95 |
| Organoleptic | |||
| Appearance | White Crystals.Its solutions are neutral to litmus. | Conforms | |
| Solubility | Freely soluble in water and in alcohol. | Conforms | |
| Physical Characteristics | |||
| Melting Range | 128-131deg.c | As per USP 37 | 129.1-129.2 deg.c |
| Identification | |||
| a) Infrared absorption | Infrared matches that of a similar preparation of USF Niacinmide RS | As per USP 37 | Conforms |
| b) U.V.Absorption | Ultraviolet spectrummatches that of similar preparation of Niacinamide Reference
Standard0.63<=A245/A262< 0.67 |
CP2010IA | Conform |
| Loss on drying | Not more than0.5% w/w | As per USP 37 | Conform |
| Residue on ignition | Not more than 0.1%w/w | As per USP 37 | Conform |
| Readily Carbonizable Substances | To comply | As per USP 37 | Conform |
| Particle Size(Granular grade) | Min.98%thru’20 mesh(ASTM) Max.10%thru140mesh(ASTM) | As per ASTM sieves | |
| Heavy metals | |||
| Lead(Pb) | Not more than 30 ppm | ICP-MS | Conform |
| The product complies with official monograph of USP 37 | |||
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