Description
The active ingredient in senna extract powder is called sennoside. The laxative effect of sennoside and its active metabolite rhein anthrone is believed to inhibit the absorption of water and electrolyte in the large intestine, thereby increasing the volume and pressure of intestinal contents. It will stimulate the push-type tightening movement of the colon.senna extract powder the Sennoside can be prepared as enema or suppository or mixed with stool softener or lumpy fibrous laxative to form a combined laxative.
Sennosides Specification
| Product Name | Senna Leaf Extract |
| Appearance | Brown powder |
| Purity | 10:1 , 20:1, sennoside A,+sennoside B 6%, 8%, 20% |
| Test Method | UV, HPLC |
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Sennosides COA
| Item | Specification Method | Result | Method |
| Physical and Chemical Property | |||
| Appearance | Brown Powder | Conforms | Visual |
| Particle Size | ≥95% through 80 mesh | Conforms | Screening |
| Residue on Ignition | ≤5g/100g | 3.52g/100g | 3g/550℃/4hrs |
| Loss on Drying | ≤5g/100g | 3.05g/100g | 3g/105℃/2hrs |
| Identification | Conforms with TLC | Conforms | TLC |
| Content: | Sennoside≥ 8% | 8.08% | HPLC |
| Residue Analysis | |||
| Heavy Metals | ≤10mg/kg | Conforms | |
| Lead (Pb) | ≤3.00mg/kg | Conforms | ICP-MS |
| Arsenic (As) | ≤2.00mg/kg | Conforms | ICP-MS |
| Cadmium (Cd) | ≤1.00mg/kg | Conforms | ICP-MS |
| Mercury (Hg) | ≤0.50mg/kg | Conforms | ICP-MS |
| Microbiological Tests | |||
| Total Plate Count | ≤1000cfu/g | 200cfu/g | AOAC 990.12 |
| Total Yeast & Mold | ≤100cfu/g | 10cfu/g | AOAC 997.02 |
| E.Coli. | Negative/10g | Conforms | AOAC 991.14 |
| Salmonella | Negative/10g | Conforms | AOAC 998.09 |
| S.aureus | Negative/10g | Conforms | AOAC 2003.07 |
Flow Chat of Sennoside
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